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Abstract
A simple and efficient synthesis of title compounds has been accomplished by regioselective 1,3-dipolar cycloaddition reaction of azomethine ylide generated by the decarboxylative condensation of isatin and sarcosine with (E)-2-arylidene-1-cyclohexanones. The regio and stereochemistry of products were determined by spectroscopic techniques. The synthesis proceeds in good yield to afford a series of novel dispiro[oxindole-cyclohexanone]pyrrolidines, 1-N-methyl-spiro-[2.31]oxindole-spiro[3.211]111-cyclohexanone-4-aryl-pyrrolidines.
Acknowledgments
AAR thanks Council of Scientific and Industrial Research (CSIR), New Delhi for the award of senior research fellowship. Financial support from CSIR and UGC, New Delhi is gratefully acknowledged.
