Synthesis of Functionalized 2,3-Dihydropyrroles Promoted by Samarium Diiodide

Abstract

The intermolecular reductive coupling of 1,1-diaryl-2,2-dicyanoethylenes or 1,1-diaryl-2-cyano-2-ethoxycarbonylethylenes with substituted benzalazines induced by samarium diiodide was studied. Functionalized 2,3-dihydropyrroles were prepared in good yields under neutral and mild conditions.

Keywords:

• Samarium diiodide
• Reductive coupling
• Electron- deficient olefin
• 2, 3-dihydropyrroles

Acknowledgments

We are grateful to the National Natural Science Foundation of China (Project No. 20072033) and the NSF of Zhejiang province for financial support.