One-Pot Synthesis of dl-2-Amino-2-thiazoline-4-carboxylic Acid

Richeng Xuan Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. ChinaCorrespondence[email protected]

Weixiao Hu Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. China

Zhongyu Yang Institute of Pharmaceutical Engineering, Zhejiang University of Technology, Hangzhou, P.R. China

Abstract

dl-2-Amino-2-thiazoline-4-carboxylic acid was prepared in one-pot reaction from 2,3-dichloropropionic acid. Not only the procedure was simplified, but also the yield was increased from less than 63% recorded to 93%.

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One-Pot Synthesis of dl-2-Amino-2-thiazoline-4-carboxylic Acid

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One-Pot Synthesis of dl-2-Amino-2-thiazoline-4-carboxylic Acid

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