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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 7
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Original Articles

An Efficient Method for the Synthesis of (+)-Cyclozonarone, Isozonarol Δ,8,9 and Isozonarone Δ8,9

José Villamizar Centro de Química, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, VenezuelaCorrespondence[email protected]
,
Juan Fuentes Centro de Química, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, Venezuela
,
Eleonora Tropper Centro de Química, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, Venezuela
,
Angel L. Orcajo Centro de Química, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, Venezuela
&
Randolph Alonso Centro de Química, Instituto Venezolano de Investigaciones Científicas (I.V.I.C.), Caracas, Venezuela
Pages 1121-1129 | Received 15 May 2002, Published online: 21 Aug 2006
 
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Abstract

An efficient method for the synthesis of (+)-cyclozonarone 5, isozonarol Δ8,9 6 and isozonarone Δ8,9 7 via the diene 4, obtained in two steps from manool 3, is described.

Acknowledgments

We thank Dr. T. Nakano for his continued interest in this work and Dr. L. Mitscher (University of Kansas) for the measurement of mass spectra. This research was supported by grant from FONACIT (S1 96001367).

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Related Research Data

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