Abstract
An efficient method for the synthesis of (+)-cyclozonarone 5, isozonarol Δ8,9 6 and isozonarone Δ8,9 7 via the diene 4, obtained in two steps from manool 3, is described.
Acknowledgments
We thank Dr. T. Nakano for his continued interest in this work and Dr. L. Mitscher (University of Kansas) for the measurement of mass spectra. This research was supported by grant from FONACIT (S1 96001367).