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The microwave-enhanced synthesis of 10-substituted isoalloxazines is achieved rapidly (˜4 min) and in good yield (>80–95%) via the cyclocondensation of 2-substituted aminoanilines with alloxan or N-methylalloxan monohydrate in the presence of acidic alumina or montmorillonite clays (KSF and K10).
Financial assistance as SRF to RS by UGC and JRF to G by CSIR, New Delhi, India is gratefully acknowledged.
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