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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 7
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Original Articles

Microwave-Assisted Synthesis of 10-Substituted Isoalloxazines in the Presence of Solid Acids

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Pages 1179-1184 | Received 15 May 2002, Published online: 21 Aug 2006
 

Abstract

The microwave-enhanced synthesis of 10-substituted isoalloxazines is achieved rapidly (˜4 min) and in good yield (>80–95%) via the cyclocondensation of 2-substituted aminoanilines with alloxan or N-methylalloxan monohydrate in the presence of acidic alumina or montmorillonite clays (KSF and K10).

Acknowledgments

Financial assistance as SRF to RS by UGC and JRF to G by CSIR, New Delhi, India is gratefully acknowledged.

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