Facile Synthesis of Oxazoles Starting from Ketones

Abstract

A new and efficient method for the preparation of 2,4- and 2,4,5-substituted oxazoles is described which is based upon the reaction of α-sulfonyloxy ketone intermediates with acetamide or benzamide.

Keywords:

• Amide
• Hypervalent iodine
• Ketone
• Oxazole

Acknowledgment

This work was supported by the Chung-Ang University research grant in 2002.