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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 12
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Original Articles

The Oxidation of Primary Alcohols to Methyl Esters and Diols to Lactones Using Trichloroisocyanuric Acid

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Pages 2003-2009 | Received 17 Oct 2002, Published online: 17 Aug 2006
 

Abstract

Primary alcohols and diols are easily oxidized to methyl esters by a solution of trichloroisocyanuric acid with methyl alcohol in dichloromethane. In addition, α,ω-diols are also readily oxidized into lactones by refluxing with trichloroisocyanuric acid and pyridine in dichloromethane.

Acknowledgment

This work was supported in part by an NSF-REU Program grant, a CSUF Undergraduate Research and Creativity Award, and an award from the Rohm and Haas Company: Otto Haas Award for Technical Excellence (courtesy of Robert K. Barr).

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