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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 13
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Original Articles

Highly Diastereoselective Alkylation of the Dellaria Oxazinone Template with Bifunctional Electrophiles

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Pages 2197-2208 | Received 08 Nov 2002, Published online: 17 Aug 2006
 

Abstract

This study investigates the efficiency of alkylation of the Dellaria oxazinone glycinate template with sensitive bifunctional electrophiles. In addition to improved access to the template, triflate/halide bifunctional combinations provided good yields (85–93%) of highly diastereoselective alkylation products.

Acknowledgment

The authors acknowledge the support of Murdoch University for this work.

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