Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 13
211
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

The Anion of 3-Methyl-2-pyridin-4-yl- 1,3-oxazine

, , &
Pages 2263-2268 | Received 09 Sep 2002, Published online: 17 Aug 2006
 

Abstract

n-Butyllithium at −78°C readily abstracts the methine proton from the title compound. The anion reacts efficiently with a range of electrophiles to provide 4-pyridyl ketones upon acid hydrolysis.

Acknowledgment

We thank Professor Keith Jones for helpful advice and comments.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.