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Abstract
A facile synthesis of 2-aroylindoles by the oxidation of 3-substituted 2-arylmethylindoles using Sarett reagent has been reported. The phenylthio group at 3-position has been cleaved by Raney nickel.
Acknowledgments
The authors thank UGC-SAP for instrument grants to the Department of Organic chemistry, University of Madras, Amrutanjan Ltd. for providing lab facilities to NA, Prof. D. Velmurugan, Dept. of Biophysics and Crystallography, University of Madras for x-ray analysis of carboxilic acid derivative of 3a and Dr. R. Murugesan, RSIC, IIT, Chennai for mass spectra.