Microwave Assisted Pictet–Spengler and Bischler–Napieralski Reactions

Abstract

Pictet–Spengler and Bischler–Napieralski reaction products have been prepared–using microwave irradiation on silicagel support under solvent free condition. Microwave assisted reactions have resulted in better yields of the desired products than prepared under conventional conditions.

Keywords:

• Microwave
• Indole
• Isoquinoline
• β-carboline
• Pictet–Spengler
• Bischler–Napieralski