A Facile Synthesis of 1,4-Diacylbenzenes

Abstract

An efficient method for the synthesis of 1,4-diacylbenzenes has been developed employing bis-tetrabutylammonium dichromate as an oxidant. By this methodology, a series of aldehydes and ketones have been synthesised under mild reaction conditions in moderate yields.

Keywords:

• Benzylic bromides
• Diacylbenzenes
• Indole-2-aldehydes
• Tetrabutyl ammonium dichromate
• Benzophenones

Acknowledgment

The authors acknowledge the financial support for this work from DST and UGC-SAP for instrument grants to the department. The authors thank Prof. T. Ishiyama of Hokkaido University, Japan for providing the IR and NMR spectra of compound 4d.