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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 18
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Original Articles

A Convenient “One-Pot” Reaction for Selective Monoalkylation of N,N′-Disubstituted Ethylenediamines

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Pages 3193-3204 | Received 18 Dec 2002, Published online: 17 Aug 2006
 

Abstract

A study on the scope of the method to obtain N,N,N′-trisubstituted ethylenediamines III by monoalkylation of N,N′-disubstituted ethylenediamines I through a “one-pot” reaction is presented. It involves condensation of compounds I with aldehydes followed by reduction of the formed imidazolidines II without previous isolation.

Acknowledgment

This work was financially supported by the Universidad de Buenos Aires and CONICET.

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