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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 33, 2003 - Issue 22
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Original Articles

Iodoform, a New Reagent in the Todd-Atherton Reaction

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Pages 3851-3859 | Received 08 Apr 2003, Published online: 19 Aug 2006
 

Abstract

An innovative and convenient application of the iodoform (1) as the reagent in the synthesis of phosphoramidates via Todd-Atherton reaction is described. The full stereoselectivity of this transformation using a 4-methyl-1,3,2-dioxaphosphinane model system was demonstrated.

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