Abstract
Simultaneous de-O-xylylation and reductive coupling was observed when 1 equiv. of the dialdehyde 2a/2b was treated with 5 equiv. of each TiCl4 and Zinc which lead to the development of TiCl4 in dioxane as a new system for the facile deprotection of phenolic ethers 4a–4d, 5a–5d, and 6a–6c.
Acknowledgment
The authors thank Ms. P. Vasumathi for her help during this investigation. VM thanks CSIR, New Delhi for financial assistance and the authors thank DST, New Delhi and UGC-SAP for financial assistance.