High-Throughput Synthesis of Alkylbenzophenones with Indium Triflate in the Absence of Solvents Using Microwave

Abstract

A series of alkylbenzophenones were rapidly and efficiently prepared from alkylbenzenes and benzoyl chlorides by Friedel-Crafts acylation catalyzed with indium triflate under solvent-free conditions by microwave heating.

Keywords:

• Microwave-assisted synthesis
• Friedel-Crafts acylation
• Alkylbenzophenones
• Indium triflates
• Solvent-free synthesis

Acknowledgment

This work was supported by grants from the Ministry of Education, Science, Sports, and Culture of Japan.