Synthesis of Selectively Protected Genistein Derivatives

Wiesław Szeja Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland

Gabriela Pastuch Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland

Ilona Wandzik Faculty of Chemistry, Silesian University of Technology, Gliwice, PolandCorrespondence[email protected]

Nikodem Kuźnik Faculty of Chemistry, Silesian University of Technology, Gliwice, Poland

Grzegorz Grynkiewicz Pharmaceutical Research Institute, Warszawa, Poland

Abstract

Differential functionalization of the phenolic groups in Genistein by sequential silylation/acylation reactions, involving some unexpected regioselective O-silyl group replacement, is described.

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Acknowledgment

Partial financial support of the State Committee for Scientific Research (KBN, grant 4 T09A 075 23) is gratefully acknowledged.

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Synthesis of Selectively Protected Genistein Derivatives

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