A Facile and Efficient Synthesis of 2,2‐Bis(3′/2′‐indolyl)ethylamines and Three Bisindolic Natural Products

Abstract

A simple and efficient synthesis of bis(indolyl)ethylamines and three bisindolic natural products, viz. hallucinogenic 6, genotoxic 7 and the alkanoic acid 8 has been developed by the reaction of indoles with appropriate carbonyl compounds on montmorillonite K10 clay.

Keywords:

• Synthesis
• Bis(indolyl)ethylamines
• Bisindolic natural products
• Streptindole

Acknowledgments

The authors sincerely thank the Director, Bose Institute for laboratory facilities, the C.S.I.R., Govt. of India for providing fellowships (N.G., R.K.B.), Mr. B. Majumder, NMR Laboratory, B.I. and Mr. P. Dey, Microanalytical Laboratory, B.I. for recording the spectra.