Directing Effect of Axial and Equatorial Anomeric Substituent in Site Specific Glycosylation of Glucopyranosides

Abstract

Regio‐ and stereoselective glycosylation of α‐ and β‐octyl glucopyranoside derivatives 2c and 2d, respectively, with glycosyl donor 3 to obtain the corresponding 3‐O‐linked 5c and 2‐O‐linked 4d saccharides, respectively, is described, formation of diglycosylated products 6c and 6d was not observed.

Keywords:

• Octyl glucopyranoside
• 2‐Pyridyl‐1‐thioglucopyranoside
• Iodomethane
• Regioselective glycosylation