Graphical Abstracts

Abstract

Synth. Commun. 2004, 34, 1753

Partial Oxidation of Alcohols to Aldehydes and Ketones Under Mild Conditions

Guang Qian, Rui Zhao, Gaomeng Lu, Yanxing Qi,* and Jishuan Suo

Lanzhou Institute of Chemical Physics, The Chinese Academy of Sciences, Lanzhou, P.R. China

A number of aldehydes and ketones were prepared by partial oxidation of alcohols in air catalyzed by RuO₂/ZSM‐5 which can be easily prepared with the industrial grade ZSM‐5 and RuCl₃ · xH₂O.

Abstract

Synth. Commun. 2004, 34, 1759

Facile Synthesis of Substituted Quinazolin‐4‐(3H)‐Ones Using Low‐Valence Titanium Reagent

Daqing Shi^1,2,3,* Liangce Rong,¹ Juxian Wang,¹ Qiya Zhuang,¹ Xiangshan Wang,¹ and Hongwen Hu²

¹Department of Chemistry, Xuzhou Normal University, Xuzhou, P.R. China

²Department of Chemistry, Nanjing University, Nanjing, P.R. China

³Key Laboratory of Biotechnology on Medical Plant, Jiangsu, Xuzhou, P.R. China

A short and facile synthesis of a series of 3‐aryl quinazolin‐4‐(3H)‐ones was accomplished in good yields via the intermolecular reductive coupling reaction of N‐aryl‐2‐nitrobenzamide and triethyl orthoformate promoted by TiCl₄/Zn.

Abstract

Synth. Commun. 2004, 34, 1767

Ultrasonic Activation for the N → O Phosphoryl Migration of Phosphoryl‐Serine and ‐Threonine

Jian Chen Zhang,¹ Shu Xia Cao,¹ Xin Cheng Liao,¹ Ling Bo Qu,¹ and Yu Fen Zhao^1,2,*

¹Department of Chemistry, The Key Laboratory of Chemical Biology, Zhengzhou University, Zhengzhou, Henan, P.R. China

²Department of Chemistry, School of Life Science and Engineering, The Key Laboratory for Bioorganic Phosphorus Chemistry and Chemical Biology, Ministry of Education, Tsinghua University, Beijing, P.R. China

A facile and efficient approach for the preparation of O‐diisopropyloxyphosphoryl‐serine and ‐threonine from their corresponding N‐diisopropyloxyphosphoryl‐serine and ‐threonine under ultrasonic activation in acetonitrile was developed in good yields. N‐(diisopropyloxyphosphoryl)‐serine and ‐threonine were prepared in high yields by using diisopropyl phosphite as the phosphorylating agent, sodium hypochlorite as the chlorinating agent and tetrabutyl ammonium bromide as the phase transfer catalyst in basic aqueous media.

Abstract

Synth. Commun. 2004, 34, 1775

Efficient Transformation of Aldoximes to Nitriles Using 2‐Chloro‐1‐Methylpyridinium Iodide Under Mild Conditions

Kieseung Lee,* Sang‐Bae Han, Eun‐Mi Yoo, Soon‐Ryang Chung, Haibum Oh, and Sungwan Hong

Department of Chemistry, Woosuk University, Chonbuk, South Korea

Abstract

Synth. Commun. 2004, 34, 1783

Solvent‐Free Synthesis of 1,5‐Benzothiazepines and Benzodiazepines on Inorganic Supports

Mitsuo Kodomari,^1,* Tomohiro Noguchi,¹ and Tadashi Aoyama²

¹Department of Applied Chemistry, Shibaura Institute of Technology, Shibaura, Minato‐ku, Tokyo, Japan

²Department of Materials and Applied Chemistry, Faculty of Science and Engineering, Nihon University, Chiyoda‐ku, Tokyo, Japan

Chalcones reacted with o‐aminothiophenol in the presence of silica gel to give 1,5‐benzothiazepines and with o‐phenylenediamine in the presence of alumina to give 1,5‐benzothiazepines in good yields under solvent‐free conditions.

Abstract

Synth. Commun. 2004, 34, 1791

Synthesis of 7‐Alkoxy/Hydroxy‐α‐methyltryptamines

Nauzer P. Dubash, Naveen K. Mangu, and Apparao Satyam*

Discovery Chemistry Division, Glenmark Research Centre, Glenmark Pharmaceuticals Ltd., Mahape, Navi Mumbai, India

A simple method for the synthesis of 7‐alkoxy/hydroxy‐α‐methyltryptamines has been developed from cheap or easily synthesizable starting materials as shown in the scheme.

Abstract

Synth. Commun. 2004, 34, 1801

First General Solvent‐Free Synthesis of Symmetrical Triindolylmethanes Using Acid‐Washed Montmorillonite Clay

Manas Chakrabarty,^1,* Sandipan Sarkar,¹ Anthony Linden,² and Bridget K. Stein³

¹Department of Chemistry, Bose Institute, Kolkata, India

²Institute of Organic Chemistry, University of Zürich, Zürich, Switzerland

³EPSRC National Mass Spectrometry Service Centre, Chemistry Department, University of Wales, Swansea, Swansea, UK

Abstract

Synth. Commun. 2004, 34, 1811

Facile Synthesis of 2′‐N‐acylamino‐m‐terphenyls via Suzuki Coupling

Perumal Rajakumar* and Muthialu Srisailas

Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India

Abstract

Synth. Commun. 2004, 34, 1819

Solid Phase One Step Synthesis of 4H, 4′‐Exomethylene‐bis[Quinazolin‐2‐Enols]

B. A. Ganai, Summon Koul,* T. K. Razdan and C. S. Andotra

Department of Chemistry, University of Jammu, Jammu, India

Abstract

Synth. Commun. 2004, 34, 1825

A facile synthesis of dispiro[oxindole‐cyclohexanone] pyrroloisoquinoline by formal 1,3‐dipolar cycloaddition strategy

G. Subramaniyan and R. Raghunathan*

Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India

Abstract

Synth. Commun. 2004, 34, 1831

Conventional and Microwave Assisted Hydrogenolysis Using Zinc and Ammonium Formate

G. R. Srinivasa, S. N. Narendra Babu, C. Lakshmi and D. Channe Gowda*

Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka, India

The selective deprotection of several N‐Bzl amino derivatives to the corresponding amines and the removal of S‐Bzl and O‐Bzl groups from the protected amino acids with ammonium formate and commercial zinc dust is reported.

Abstract

Synth. Commun. 2004, 34, 1839

Facile Synthesis Of 1,1‐Diacetates from Aldehydes Using Environmentally Benign Solid Acid Catalyst Under Solvent‐Free Conditions

Benjaram M. Reddy,* Pavani M. Sreekanth, and Ataullah Khan

Inorganic and Physical Chemistry Division, Indian Institute of Chemical Technology, Hyderabad, India

Synthesis of diacetates from aldehydes in presence of environmentally benign Mo/TiO₂–ZrO₂ solid acid catalyst under solvent free conditions

Abstract

Synth. Commun. 2004, 34, 1847

Synthesis of Novel Schiff's Bases Containing Pyridine Rings

S. J. Swamy,* K. Suresh, P. Someshwa and D. Nagaraju

Department of Chemistry, Kakatiya University, Warangal, India

Synthesis of new Schiff's bases, the potential hexadentate ligands containing amide groups and pyridine rings with shallow structures are described. The two step reactions involving ring opening of isatoic anhydride with diamines followed by condensation with pyridine aldehydes in presence of PTSA yield title compounds in high purity and good yields.

Abstract

Synth. Commun. 2004, 34, 1855

Synthesis of Monocyclic β‐Lactams Via Cyclodehydration of β‐Amino Acids Using POCl₃

S.D. Sharma,* R.D. Anand, and Gurpreet Kaur

Department of Chemistry, Panjab University, Chandigarh, India

β‐Lactams 2 have been synthesized through a convenient use of POCl₃ via cyclodehydration of β‐amino acids 1.

Abstract

Synth. Commun. 2004, 34, 1863

A Preferred Synthesis of 1,2,4‐Oxadiazoles

Brenda Pipik,* Guo‐Jie Ho, J. Michael Williams and David A. Conlon

Department of Process Research, Merck Research Laboratories, Rahway, New Jersey, USA

An efficient and high‐yielding one‐pot synthesis of 1,2,4‐oxadiazoles from carboxylic acids and amidoximes is described.

Abstract

Synth. Commun. 2004, 34, 1871

Acylative Dimerization of Tetrahydrofuran Catalyzed by Rare‐Earth Triflates

William H. Miles,* Daniel A. Ruddy, Samira Tinorgah, and Rebecca L. Geisler

Department of Chemistry, Lafayette College, Easton, Pennsylvania, USA

Abstract

Synth. Commun. 2004, 34, 1881

A Facile Synthesis of [Tetrahydrofuran‐³H] Terazosin

Judith A. Egan, Steven M. Souza and Crist N. Filer*

PerkinElmer Life and Analytical Sciences, Inc., Boston, Massachusetts, USA

An efficient synthesis of [³H] terazosin at high specific activity from prazosin is described.

Abstract

Synth. Commun. 2004, 34, 1885

Synthesis of Hexabutylditin from Tributyltin Hydride and bis(Tributyltin)oxide

Alla Darwish and J. Michael Chong*

Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada

Heating a mixture of tributyltin hydride (>2 mol equiv.) and bis(tributyltin)oxide cleanly produces hexabutylditin in excellent yield.

Abstract

Synth. Commun. 2004, 34, 1891

A Convenient Synthesis of 2‐(9H‐Fluoren‐9‐ylmethoxycarbonylamino)‐thiazole‐4‐carboxylic Acid Via N‐Fmoc‐thiourea

Kang Le and Robert A. Goodnow Jr.*

Roche Research Center, Hoffmann‐La Roche, Inc., Nutley, New Jersey, USA

2‐(9H‐Fluoren‐9‐ylmethoxycarbonylamino)‐thiazole‐4‐carboxylic acid has been prepared in high yield from 3‐bromopyruvic acid and (aminothioxomethyl)carbamic acid 9H‐fluoren‐9‐ylmethyl ester (N‐Fmoc‐thiourea) which was obtained from potassium thiocyanate.

Abstract

Synth. Commun. 2004, 34, 1897

An Improved Synthesis of PET Dopamine D₂ Receptors Radioligand [¹¹C]Raclopride

Xiangshu Fei, Bruce H. Mock, Timothy R. DeGrado, Ji‐Quan Wang, Barbara E. Glick‐Wilson, Michael L. Sullivan, Gary D. Hutchins, and Qi‐Huang Zheng*

Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA

An improved synthesis of PET dopamine D₂ receptors radioligand [¹¹C]raclopride has been developed.

Abstract

Synth. Commun. 2004, 34, 1909

A Single‐Step Assembly of Coumarin Ring Skeleton from Oxygenated Phenols and Acetylenic Esters by Catalytic Indium Chloride in the Absence of Solvent

N. Kalyanam,* A. Nagarajan, and M. Majeed

Research and Development, Sabinsa Corporation, Monmouth Junction, New Jersey, USA

Abstract

Synth. Commun. 2004, 34, 1915

One‐Pot Synthesis of Pyrazole‐5(3)‐carboxyamides

M. A. P. Martins,* D. Emmerich, P. Beck, W. Cunico, C. M. P. Pereira, A. P. Sinhorin, S. Brondani, R. Peres, M. V. M. Teixeira, H. G. Bonacorso, N. Zanatta

NUQUIMHE, Depto. de Química, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil

A convenient one‐pot synthesis of eight pyrazole‐5(3)‐carboxyamides from the reaction of the 5(3)‐trichloromethylpyrazoles with amines is reported.