Chemistry of L‐Ascorbic Acid. IV. Regioselective O‐Alkylation of 5,6‐O‐Isopropylidene‐L‐ascorbic Acid Using CsF

Abstract

The regioselective 3‐O‐alkylation of 5,6‐O‐isopropylidene‐L‐ascorbic acid is achieved under mild conditions using CsF as a base.

^#See Ref.1.

Keywords:

• L‐Ascorbic acid (vitamin C)
• Alkyl halides
• O‐Alkylation
• Ethers
• Cesium fluoride

Acknowledgment

The authors thank CSIR, New Delhi, India for financial support as well as assistantship to SDK.

Notes

^#See Ref.1.