A Novel Route to 3‐(O,O‐Diethylphosphoryl)‐2,3‐dihydrofurans via Rhodium‐Catalyzed Heterocycloaddition Reaction

Abstract

A series of 3‐phosphoryl‐2,3‐dihydrofurans are efficiently synthesized by the reaction of diethyl 1‐diazo‐2‐oxo‐alkylphosphonates with alkyl vinyl ethers in good yields. 2,3‐Dihydrofurans bearing phosphoryl and trifluoromethyl moieties are also prepared in a similar manner.

^#Studies on Organophosphorus Compounds, Part 132. For Part 131, see D. Gong, L. Zhang and C. Yuan, Synthetic Commun. 2004, 34 (18).

Keywords:

• Heterocycloaddition
• Phosphoryl dihydrofurane
• Rhodium‐catalyzed

Acknowledgment

The project was supported by the National Natural Science Foundation of China (grant no. 20272075 and 20372076).

Notes

^#Studies on Organophosphorus Compounds, Part 132. For Part 131, see D. Gong, L. Zhang and C. Yuan, Synthetic Commun. 2004, 34 (18).