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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 18
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Original Articles

Potassium 2‐Cyanoethylene‐1‐thiolate Derivatives: A New Preparative Route to 2‐Cyanoketene S,N‐Acetals and Pyrazole Derivatives

Galal H. Elgemeie Chemistry Department, Faculty of Science, Helwan University, Helwan, Cairo, EgyptCorrespondence[email protected]
,
Ahmed H. Elghandour Chemistry Department, Faculty of Science, Cairo University, Beni‐Suef Branch, Beni‐Suef, Egypt
&
Ghada W. Abd Elaziz Chemistry Department, Faculty of Science, Cairo University, Beni‐Suef Branch, Beni‐Suef, Egypt
Pages 3281-3291 | Received 21 Jun 2002, Published online: 12 Jan 2011
 
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Abstract

The novel ketene S,N‐acetals 4a–e were readily prepared by the reaction of substituted cyanoacetanilides with phenylisothiocyanate in the presence of potassium hydroxide, followed by alkylation of the produced salts with methyl iodide. The reaction of compounds 4 with hydrazines afforded different substituted pyrazoles.

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Related Research Data

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