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Abstract
A rapid and convenient preparation of 7‐(alkyl/aralkyl)guanines from guanosine is described. Using this method, a series of 7‐substituted guanines (compounds 2a–k) was synthesized in good yields (51%–97%).
Notes
aThe NH proton in 2a, 2b, 2g, 2h, 2i, and 2k were not distinctly observed in the 1H NMR spectra presumably due to rapid exchange with traces of water.