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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 19
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Original Articles

Efficient Tetrahydropyranylation of Alcohols and Detetrahydropyranylation Reactions in the Presence of Catalytic Amount of Trichloroisocyanuric Acid (TCCA) as a Safe, Cheap Industrial Chemical

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Pages 3623-3630 | Received 07 Jul 2003, Published online: 10 Jan 2011
 

Abstract

Preparation and cleavage of THP ethers of different hydroxy functional groups are easily and efficiently performed in the presence of trichloroisocyanuric acid (TCCA) in the absence of solvent with high yields.

Acknowledgment

The authors are grateful for the partial support of this work by the Shiraz University Research Council. The valuable help of K. Amani and S. Ghassamipour for repeating some of the reactions is gratefully acknowledged.

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