Abstract
A concise and efficient synthesis of (R)‐ and (S)‐2‐methylpiperazine in only five steps from (D)‐ and (L)‐alanine is described. The key step is reaction of benzylamine with a bifunctional molecule to build a six‐membered ring.
Keywords:
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 22
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