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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 34, 2004 - Issue 24
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Original Articles

Synthesis of Novel 5‐Trifluoromethyl‐2,4,7‐Trisubstituted Pyrido[2,3‐d]Pyrimidines

, , , , &
Pages 4463-4469 | Received 28 Aug 2004, Published online: 10 Jan 2011
 

Abstract

Novel pyrido[2,3‐d]pyrimidines (2,4) were synthesized by reacting 2‐amino‐3‐cyano‐4‐trifluoromethyl‐6‐substituted pyridines (1) with Grignard reagent followed by condensation with anhydride/chloroacetylchloride/aromatic aldehyde.

aIICT Communication No.: 040104.

Acknowledgment

The authors are thankful to S. Narayan Reddy, for his constant encouragement and to CSIR, New Delhi for financial support in the form of a senior research fellowship to SRK.

Notes

aIICT Communication No.: 040104.

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