1‐Benzyl‐4‐Aza‐1‐Azoniabicyclo[2.2.2]Octane Tribromide as a Highly Reactive Brominating Agent for Aniline Derivatives

Abstract

Reaction of anilines with 1‐benzyl‐4‐aza‐1‐azoniabicyclo[2.2.2]octane tribromide (3) in the presence of CaCO₃ in small amounts of methanol gave brominated aromatic amines in good yields at room temperature. The isolation of products is straightforward.

Keywords:

• Aniline
• Bromination
• Tribromide

Acknowledgment

Partial support of this work by the Isfahan University of Technology (IUT), Research Council is gratefully acknowledged. Further financial support from the Center of Excellency in Chemistry Research (IUT) is gratefully acknowledged.