A Clean and Simple Synthesis of 6‐Amino‐4‐Aryl‐5‐Cyano‐3‐Methyl‐1‐Phenyl‐1,4‐Dihydropyrano[2,3‐c]Pyrazole in Water

Tong‐Shou Jin Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, P. R. ChinaCorrespondence[email protected]

Ai‐Qing Wang Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, P. R. China

Zhao‐Li Cheng Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, P. R. China

Jian‐She Zhang Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, P. R. China

Tong‐Shuang Li Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding, 071002, P. R. China

Abstract

A simple and clean method for producing 6‐amino‐4‐aryl‐5‐cyano‐3‐methyl‐1‐phenyl‐1,4‐ dihydropyrano[2,3‐c]pyrazole from aromatic aldehyde, malononitrile and 3‐methyl‐1‐phenyl‐ 2‐pyrazolin‐5‐one catalyzed by hexadecyltrimethylammonium bromide (HTMAB) in water is described. This method provides several advantages such as mild reaction conditions, simple workup procedure, and being environmentally friendly.

Keywords:

Acknowledgments

This project was supported by the National Natural Science Foundation of China (29872011 and 29572039), Educational Ministry of China, Educational Department of Hebei Province 990104, Science and Technology Commission of Hebei Province.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

A Clean and Simple Synthesis of 6‐Amino‐4‐Aryl‐5‐Cyano‐3‐Methyl‐1‐Phenyl‐1,4‐Dihydropyrano[2,3‐c]Pyrazole in Water

Information for

Open access

Opportunities

Help and information

A Clean and Simple Synthesis of 6‐Amino‐4‐Aryl‐5‐Cyano‐3‐Methyl‐1‐Phenyl‐1,4‐Dihydropyrano[2,3‐c]Pyrazole in Water

Abstract

Acknowledgments

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature