Synthesis of 3,4‐Dihydropyrimidine‐2(1H)‐thiones and Quinazolin‐4(3H)‐ones over Yb(III)‐Resin Catalyst Under Solvent‐free Conditions

Abstract

Ytterbium(III) reagent supported on ion exchange resin is applied to the multicomponent condensation reactions under solvent‐free conditions. One‐pot synthesis of a library of 3,4‐dihydropyrimidine‐2(1H)‐thiones and quinazolin‐4(3H)‐ones were described. The advantages of easy separation and recyclability of the catalysts were demonstrated.

Keywords:

• Ytterbium(III)
• resin supported
• multicomponent condensation
• 3,4‐dihydropyrimidine‐2(1H)‐thiones
• quinazolin‐4(3H)‐ones
• solvent‐free