An Approach to Double Thiacalixarene

Abstract

A new double thiacalix[4]arene and a 1,3‐disubstituted thiacalix[4]arene were obtained by refluxing p‐tert‐butylthiacalix[4]arene in benzene with 2,6‐bis(bromomethyl)‐4‐methylanisole in the presence of Na₂CO₃ as a base under argon in 58% and 10% yield, respectively.

Keywords:

• Calixarene
• biscalixarene
• thiacalixarene
• double thiacalixarene

Acknowledgment

Financial support from the National Natural Science Foundation of China (20272044) and is gratefully acknowledged.

Notes

¹It was reported that the signals of ArOCH₂ protons of 1,3‐p‐tert‐butylthiacalix[4]monocrown‐5 appeared at 4.76–4.15, and that of 1,3‐alt p‐tert‐butylthiacalix[4]monocrown‐5 dialkylethers appeared at 3.92–3.41.