Praseodymium Trifluoromethylsulfonate as an Efficient and Recyclable Catalyst for the Synthesis of α‐Aminonitriles

Surya K. De Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue Cancer Center, Purdue University, West Lafayette, Indiana, USACorrespondence[email protected]

Richard A. Gibbs Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy, Purdue Cancer Center, Purdue University, West Lafayette, Indiana, USA

Abstract

Praseodymium trifluoromethylsulfonate (triflate) has been found to be an efficient and recyclable catalyst for the synthesis of α‐aminonitrile by a one‐pot, three‐component condensation of aldehydes, amines, and trimethylsilyl cyanide at room temperature.

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Praseodymium Trifluoromethylsulfonate as an Efficient and Recyclable Catalyst for the Synthesis of α‐Aminonitriles

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Praseodymium Trifluoromethylsulfonate as an Efficient and Recyclable Catalyst for the Synthesis of α‐Aminonitriles

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