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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 11
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Original Articles

Convenient Synthesis and Reactivity of Ethyl 8‐amino‐6‐methyl‐2,3‐dihydro‐4H‐1‐benzopyran‐2‐carboxylate

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Pages 1461-1470 | Received 17 Jan 2005, Published online: 17 Dec 2010
 

Abstract

We report and comprehensively describe the synthesis and reactivity of ethyl 8‐amino‐6‐methyl‐3,4‐dihydro‐2H‐1‐benzopyran‐2‐carboxylate. This peptidomimetic building block provides a constrained template that allows for the introduction of various functionalities in a specific spatial orientation.

Acknowledgments

We thank Roger Pain for his careful reading of the manuscript and many useful suggestions.

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