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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 35, 2005 - Issue 11
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Original Articles

Synthesis of 2‐Amino‐octa‐4,7‐Dien‐1‐ol (2): Key Intermediate for Mycothiazole Natural Product and Analogs

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Pages 1481-1492 | Received 27 Jan 2005, Published online: 17 Dec 2010
 

Abstract

Starting from L‐aminoacids, facile methods for the preparation 2‐aminocta‐4,7‐dien‐ol with different stereochemistry have been developed as key intermediates of mycothiazole and analogs.

Acknowledgments

This work was supported by grants from SAREC (Swedish Agency for Research Cooperation with Developing Countries), PEDECIBA (Programa de Desarrollo de Ciencias Básicas, Project URU/84/002), and NIH/FIRCA (Fogarty International Research Collaboration Award).

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