Solvent‐Free Synthesis of Arylamides and Arylimides, Analogues of Acetylcholine

J. Trujillo‐Ferrara Escuela Superior de Medicina, Instituto Politécnico Nacional, Sección de Estudios del Posgrado e investigación y Departamento de Bioquímica, Plan de San Luis y Díaz Mirón, MéxicoCorrespondence[email protected]

José Correa‐Basurto Escuela Superior de Medicina, Instituto Politécnico Nacional, Sección de Estudios del Posgrado e investigación y Departamento de Bioquímica, Plan de San Luis y Díaz Mirón, México

Judith Espinosa Escuela Superior de Medicina, Instituto Politécnico Nacional, Sección de Estudios del Posgrado e investigación y Departamento de Bioquímica, Plan de San Luis y Díaz Mirón, México

Jazmín García Escuela Superior de Medicina, Instituto Politécnico Nacional, Sección de Estudios del Posgrado e investigación y Departamento de Bioquímica, Plan de San Luis y Díaz Mirón, México

Francisco Martínez Unidad Profesional Interdisciplinaria de Biotecnología, Instituto Politécnico Nacional, Departamento de Química, Barrio Ticomán, México

René Miranda Facultad de Estudios Superiores Cuautitlán, Departamento de Química, Universidad Nacional Autónoma de México, Col. Santa Maria de las Torres, Cuautitlán Izcalli, México

Abstract

Several arylamides and arylimides, novel inhibitors of acetylcholinesterase, were obtained under solventless conditions; the target molecules were produced with a good overall yield and short reaction times.

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Acknowledgments

The authors thank CONACYT, COFAA, and CGPI/IPN for financial support.

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Solvent‐Free Synthesis of Arylamides and Arylimides, Analogues of Acetylcholine

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