Preparation and Thermal, Spectroscopic, and Antibacterial Studies of Some Mixed‐Ligand Complexes

Abstract

The present investigation reports the synthesis, characterization, and antibacterial activities of some mixed‐ligand complexes of the type [ML(SB)H₂O], where M = Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II), SB¹ = bis(benzylidene)ethylenediamine (benen) or SB² = bis(acetophenone)ethylenediamine (acphen) and KHL = potassium salt of salicylideneglycine (salgly). Their structures have been elucidated on the basis of elemental analyses, thermogravimetric analyses, magnetic measurements, reflectance spectra, and IR spectra. The results are in accord with an octahedral environment around the central metal ion. The mixed‐ligand complexes of Mn(II), Co(II), Ni(II), and Cu(II) are paramagnetic while the Zn(II) and Cd(II) complexes are diamagnetic. The mixed‐ligand complexes have been tested against bacteria and the results are compared with a standard drug (tetracycline) and control (dimethyl sulfoxide).

Keywords:

• Mixed‐ligand complexes
• Schiff bases
• Tetracycline
• Dimethyl sulfoxide

Acknowledgments

We wish to express our sincere thanks to Prof. R. M. Patel, Head, Department of Chemistry and Prof. M. Dutta, Head, Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar, India, for providing the necessary laboratory facilities.