Synthesis, Structural Characterization, and Antibacterial Studies of Some Mixed‐Ligand First Row d‐Transition Metal Complexes

Abstract

Some mixed‐ligand complexes of the transition metal ions Mn(II), Co(II), Ni(II), Cu(II), Zn(II), and Cd(II) with the potassium salt of salicylideneglycine and 2,2′‐bipyridylamine or di(benzylidene)‐1,8‐diaminonaphthalene have been prepared. The coordination behavior of the mixed‐ligand complexes was characterized on the basis of elemental analyses, IR, and electronic spectra. The magnetic measurements have been obtained by a vibrating sample magnetometer. It is observed that the mixed‐ligand complexes of Mn(II), Co(II), Ni(II), Cu(II) are paramagnetic, while the Zn(II) and Cd(II) complexes are diamagnetic. All of these mixed‐ligand complexes are colored crystalline solids. Octahedral geometries have been assigned to all of the prepared mixed‐ligand complexes. The antibacterial activities of the ligands, the metal chlorides, the mixed‐ligand complexes, the standard drug (tetracycline), and control (dimethyl sulfoxide) were tested on the pathogenic bacteria S. typhi, E. coli, and Serratia marcescens using the “disc diffusion method,” and the results are discussed.

Keywords:

• Mixed‐ligand
• Disc diffusion method
• Schiff bases
• 2,2′‐Bipyridylamine

Acknowledgments

We wish to express our sincere thanks to Prof. R. M. Patel, Head, Department of Chemistry and Prof. M. Dutta, Head, Department of Biosciences, Sardar Patel University, Vallabh Vidyanagar, India, for providing the necessary laboratory facilities.