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Research Article

Novel Taxane Diterpenoids from Taiwanese Yew Trees

, , , , &
Pages 533-545 | Published online: 12 Nov 2003
 

Abstract

Recent discovery of new and bioactive taxane diterpenoids from the roots, barks, seeds, leaves and the stems of Taxus mairei and T. sumatrana, Taiwanese yew trees are described. More than thirty new compounds including taxumatrols A and B (36, 37) have been isolated and their structures determined by spectroscopic analysis and chemical derivatization and correlation. Some of the isolated taxoids exhibited potent cytotoxicity against human tumor cells.

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