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Abstract
Background
The retinal nerve fibre layer (RNFL) thickness is reportedly decreased in myopia; however, magnification adjustment is an important consideration when using optical coherence tomography (OCT) to evaluate myopic eyes. In this study, RNFL thickness and optic nerve head (ONH) size were measured in highly myopic eyes with and without magnification adjustments. The measurements were compared with magnification‐adjusted OCT measurements of emmetropic control eyes.
Methods
In this cross‐sectional study, RNFL thickness (global circle and quadrants) and ONH size (disc and rim areas) were measured in one eye of each of 70 participants with high myopia. Magnification‐adjusted measurements taken in the high myopes were then compared with magnification‐adjusted measurements taken in 70 emmetropic controls.
Results
Comparisons of magnification‐adjusted measurements between highly myopic and emmetropic control eyes showed that the highly myopic eyes had significantly thicker global and temporal RNFLs (p < 0.05), significantly thinner nasal (p < 0.05), and significantly larger disc and rim areas RNFL (p < 0.05). Superior and inferior RNFL thickness measurements did not differ significantly between the two groups (p > 0.05).
Conclusion
The OCT measurements obtained with magnification adjustment show global and temporal RNFL thicknesses and ONH size increase in highly myopic eyes.
Dr Chang and Dr Ko contributed equally to this work and are graded as co‐second authors.
Dr Chang and Dr Ko contributed equally to this work and are graded as co‐second authors.
Acknowledegment
The authors are grateful to Paul Steve Lugue for assistance with manuscript review and English editing.
Notes
Dr Chang and Dr Ko contributed equally to this work and are graded as co‐second authors.