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Invited Review

Epidemiology of contact lens‐induced infiltrates: an updated review

, OD MS & , OD PhD
Pages 473-481 | Received 01 Apr 2017, Accepted 11 Jul 2017, Published online: 15 Apr 2021
 

Abstract

Corneal infiltrative events (CIEs) are well established as a risk associated with soft contact lens wear. The incidence of symptomatic CIEs during extended soft lens wear ranges from 2.5 to six per cent; when asymptomatic CIEs are included, the incidence can be as high as 20–25 per cent. In daily soft lens wear, the annual incidence of symptomatic CIEs is about three per cent. There are various accepted methods of categorising CIEs, and a scoring system based on clinical signs and symptoms is a good approach to grade severity. Lens‐related risk factors include extended wear, silicone hydrogel material, the use of multipurpose solutions, bacterial bioburden and reusable lenses. Recent studies report that daily disposable lenses reduce the risk of CIEs.

ACKNOWLEDGEMENTS

This work was indirectly supported by the Ohio Lions Eye Research Foundation and Research to Prevent Blindness. Dr Szczotka‐Flynn has received research support from Alcon Laboratories and Johnson & Johnson Vision Care, Inc in the past 12-months.

Additional information

Funding

Ohio Lions Eye Research Foundation and Research
Alcon Laboratories
Johnson & Johnson Vision Care, Inc

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