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I am indebted to Gerd Maul and Paul Freemont for their thoughtful discussions of this review. I am grateful for the expertise in bioinformatics from Luce Skrabanek at the Institute for Computational Biomedicine, Mt. Sinai School of Medicine. I am grateful for critical discussions of the manuscript from Alex Kentsis, Jackie Perez, Madhulika Sharma, Stephen Strudwick, and Ivan Topisirovic.
I am a scholar of the Leukemia and Lymphoma Society. Financial support was provided by the National Institutes of Health (CA80728 and CA88991).