We are grateful to Anita Corbett and Jennifer Ball for critical review of the manuscript. We especially thank Diana Lim for design and preparation of figures. We also thank Maureen Powers for helpful discussion and Anita Corbett for communication of unpublished work. We apologize to anyone whose work was not cited due to space limitations.
C.D. is supported by a Ruth L. Kirschstein NRSA individual fellowship from the NIH. This work was also supported by NIH grant GM61275 (to K.S.U.).