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Molecular and Cellular Biology Volume 5, 1985 - Issue 7
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Research Article

Erbb Is Linked to the Alpha-Globin Locus on Mouse Chromosome 11

Jonathan Silver1 Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland20205
,
J. Barry Whitney III2 Department of Cell and Molecular Biology, Medical College of Georgia, Augusta, Georgia30912
,
Christine Kozak3 Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland20205
,
Gregory Hollis4 NCI-Navy Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland20205
&
Ilan Kirsch4 NCI-Navy Medical Oncology Branch, National Cancer Institute, Bethesda, Maryland20205
Pages 1784-1786 | Received 04 Dec 1984, Accepted 02 Apr 1985, Published online: 31 Mar 2023
 
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Abstract

A fragment of the human gene for c-erb-B was used to map homologous sequences in mice. Analysis of somatic cell hybrids and recombinant inbred and congenic mouse strains indicated that this gene, designated Erbb, is closely linked to the gene for alpha-globin on mouse chromosome 11. Several genes controlling hematopoietic differentiation map to mouse chromosome 11.

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