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Abstract
The rat α2u globulin gene family encodes approximately 20 low-molecular-weight (20,000) proteins with pIs ranging from 4.5 to 7.9. α2u globulin protein isoforms were detected in the liver and in the submaxillary, lachrymal, preputial, and mammary glands of Sprague-Dawley rats. The hormonal and developmental regulation of α2u globulin synthesis in each of these tissues was unique, and it appears that different α2u gene sets were transcribed in the various tissues.