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Research Article

Abelson Virus Abrogation of Interleukin-3 Dependence in a Lymphoid Cell Line

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Pages 4133-4135 | Received 17 Apr 1986, Accepted 03 Jul 1986, Published online: 31 Mar 2023
 

Abstract

Among several tyrosine-protein kinases, only v-abl could abrogate interleukin 3 dependence of a lymphoblastoid cell line; v-src and v-fps proteins gave partial or no interleukin 3 independence, respectively. Lymphokine independence was achieved via a nonautocrine mechanism. Direct involvement of c-myc in this process was not evident.

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