Polymerizable derivatives of (+)-1(S)-p-nitrophenyl-2(S)-amino-propane-1, 3-diol

Abstract

Template molecules have been used to generate cavities in polymer materials. If chiral template molecules are used, then it is to be expected that the prepared cavities will also be chiral. An attempt has been made to convert (+)-1(S)-p-nitrophenyl-2(S)-amino-propane-1,3-diol, a by-product in the synthesis of chloroamphenicol, into polymerizable derivatives and to incorporate these derivatives into polymers. Preferred conformations of the monomers were calculated by means of the cosmos force field. The results are compared with those of the spectroscopic characterization of the substances.

Keywords:

• (+)-1(S)-p-nitrophenyl-2(S)-amino-propane-1,3-diol
• polymerizable derivatives
• COSMOS Force Field calculations
• preferred conformations
• spectroscopic characterization