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Articles

Hemocompatible properties of polymeric derivative of paracetamol

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Pages 523-530 | Published online: 02 Apr 2012
 

Abstract

Copolymerization of NN-dirnethylacrylamide (DMAA) and p-acryloyloxiacetanilide (AOA) was carried out at different mole ratios of the monomers to obtain copolymers of varying compositions. DMAA contents were very near to the corresponding monomer feed and varied between 0.20 and 0.80. Investigation of the protein adsorption of these polymer surfaces showed that copolymers with higher DMAA content adsorbed more albumin than fibrinogen. The scanning electron micrographs of the polymer-coated coverslips after contact with blood showed an antithrombogenic behaviour of these surfaces.

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