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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 11, 2008 - Issue 3
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Research articles

Mini Nutritional Assessment in patients with Parkinson's disease: correlation between worsening of the malnutrition and increasing number of disease-years

, , , , , , , , & show all
Pages 128-134 | Published online: 19 Jul 2013
 

Abstract

Objective: To monitor the nutritional status of patients with Parkinson's disease using the Mini Nutritional Assessment (MNA) questionnaire.

Patients and methods: This was a 3-year longitudinal study conducted in a national referral centre for Parkinson's disease and other movement disorders. The cohort included 61 Parkinson's disease patients, 37 men and 24 women, mean age of 70.5 ± 5.5 years, mean duration of disease 9 ± 6.3 years; 35 patients were followed-up after 3 years.

Results: MNA score diminished from 24.9 ± 1.6 to 24 ± 2.5 (P = 0.02); the proportion of patients at risk of malnutrition increased from 22.9% to 34.3%. A linear correlation was observed between MNA score and the duration of disease (P = 0.0096). The dietary assessment subscore significantly diminished (8.6 versus 8.1; P = 0.0009) as did body mass index (25.9 ± 3.5 kg/m2 versus 27.1 ± 3.1 kg/m2; P = 0.001).

Conclusions: The evaluation of nutritional status should be part of the routine work-up of a Parkinson's disease patient. Dietary education should be included amongst the therapeutic measures designed to improve the general conditions in Parkinson's disease.

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