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Acta Clinica Belgica
International Journal of Clinical and Laboratory Medicine
Volume 64, 2009 - Issue 5
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Case reports

AUTOIMMUNE HAEMOLYTIC ANAEMIA ASSOCIATED WITH A THYMOMA: CASE REPORT AND REVIEW OF THE LITERATURE

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Pages 447-451 | Published online: 09 Jan 2014
 

Abstract

A 67-year-old female presents with a small mass in the anterior mediastinum on chest computed tomography. A biopsy proves the mass to be a spindle-cell-type or type A thymoma. Subsequently the patient develops fever and severe Coombspositive haemolytic anaemia. She is initially treated with oral corticosteroids. Because of persistence of the haemolysis subsequent thymectomy is performed. Haemolysis disappears almost instantly and does not return after discontinuation of the oral corticosteroids. Review of the literature reveals only 17 other cases of thymoma-associated autoimmune haemolytic anaemia.

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