Tissue Microarray in Melanoma

Abstract

Tissue microassay technology represents a radical improvement in our ability to visualize molecular targets in multiple tissue sections. Available at the DNA, RNA, or protein level, literally thousands of tissue samples can be analyzed in one single procedure on a single glass slide. This breakthrough has vast implications for ous ability to evaluate genes on a large scale and thereby to investigate their roles in carcinogenesis. Research in melanoma repreSentS one potential area within which this information could prove invaluable, and only just recently has tissue microarray technology been used in this pursuit. (The J Histotechno 1 26:271, 2003)

Keywords:

• tissue microarray
• melanoma
• immunohistochemistry
• cDNA
• rnicroisection